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邦纳博士计划通过更年轻、更健康的人类受害者周期性的腺移植来永生。邦纳看起来大约40岁，他真的104岁了。但是人们开始怀疑了，他可能不会到200岁。。Set inside a pre-war duplex in downtown Manhattan, The Humans follows the course of an evening in which the Blake family gathers to celebrate Thanksgiving. As darkness falls outside the crumbling building, mysterious things start to go bump in the night and family tensions reach a boiling point。